Adrenal fatigue: What causes it? (2024)

Is there such a thing as adrenal fatigue?

Answer From Ann Kearns, M.D., Ph.D.

Adrenal fatigue isn't an official medical diagnosis. It's a general term used to describe a group of symptoms that aren't specific. Examples of those symptoms include tiredness, weakness, sleep problems, and cravings for sugar and salt.

The adrenal glands are located on top of the kidneys. These glands make a variety of important hormones. When the adrenal glands don't make enough hormones, the medical term for that condition is adrenal insufficiency. It may happen due to another medical condition. Or it could be the result of surgery or other medical treatment, such as radiation or certain medicines.

Symptoms of adrenal insufficiency include:

  • Feeling very tired.
  • Body aches.
  • Loss of appetite and weight loss.
  • Nausea and vomiting.
  • Low blood pressure.
  • Lightheadedness.
  • Loss of body hair.
  • A change in skin color, also called hyperpigmentation.
  • Craving salt.
  • Depression.

Adrenal insufficiency can be diagnosed with tests that check the level of adrenal hormones in the body. Imaging exams such as a CT scan or an MRI may be useful too.

Some people claim that adrenal fatigue is a mild form of adrenal insufficiency caused by chronic stress. The idea is that the adrenal glands can't keep up with the demands of the ongoing fight-or-flight state in the body that chronic stress causes. Existing blood tests, according to this theory, aren't sensitive enough to detect a small drop in adrenal function., but that drop triggers the symptoms of adrenal fatigue. However, there is no evidence to support this theory.

Dealing with symptoms that last can be frustrating, especially if your healthcare team can't explain them. But accepting that symptoms are caused by a vague label, such as adrenal fatigue, could cause the true source of a problem to go without a diagnosis or treatment. And that can take a serious toll on your body over time.

If you have symptoms that don't go away, talk to your healthcare team about possible causes. Discuss tests that might be useful, as well as lifestyle changes and treatment that could help you feel better.

With

Ann Kearns, M.D., Ph.D.

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  • Salt craving: A symptom of Addison's disease?

April 10, 2024

  1. Adrenal fatigue. Endocrine Society. https://www.endocrine.org/patient-engagement/endocrine-library/adrenal-fatigue. Accessed Dec. 7, 2023.
  2. Cadegiani FA, et al. Adrenal fatigue does not exist: A systematic review. BMC Endocrine Disorders. 2016; doi:10.1186/s12902-016-0128-4.
  3. Adrenal insufficiency and Addison's disease. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/endocrine-diseases/adrenal-insufficiency-addisons-disease. Accessed Dec. 7, 2023.
  4. AskMayoExpert. Adrenal insufficiency (adult). Mayo Clinic; 2022.
  5. Nieman LK. Clinical manifestations of adrenal insufficiency in adults. https://www.uptodate.com/contents/search. Accessed Dec. 7, 2023.
  6. Nieman LK, et al. Diagnosis of adrenal insufficiency in adults. https://www.uptodate.com/contents/search. Accessed April 1, 2020.

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Adrenal fatigue: What causes it? (2024)

FAQs

Adrenal fatigue: What causes it? ›

When the adrenal glands don't make enough hormones, the medical term for that condition is adrenal insufficiency

adrenal insufficiency
Overview. Addison's disease, also called adrenal insufficiency, is an uncommon illness that occurs when the body doesn't make enough of certain hormones. In Addison's disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone.
https://www.mayoclinic.org › symptoms-causes › syc-20350293
. It may happen due to another medical condition. Or it could be the result of surgery or other medical treatment, such as radiation or certain medicines.

What is the root cause of adrenal fatigue? ›

According to the theory of adrenal fatigue, when people are faced with long-term stress, their adrenal glands cannot keep up with the body's need for these hormones. It is when this happens that supporters of adrenal fatigue believe that symptoms may appear.

What is bad for adrenal fatigue? ›

If you decide to try a diet for adrenal fatigue, it's generally recommended to limit foods and drinks high in refined and processed sugar and unhealthy fats. Some foods to limit include: white sugar. white flour.

What vitamin deficiency causes adrenal fatigue? ›

More specifically, vitamin C is needed for the production of cortisol in the adrenal glands. Consequently, when vitamin C levels are low, the body cannot produce the necessary amount of cortisol when combatting stress. This results in adrenal fatigue.

What can mimic adrenal fatigue? ›

And it says the symptoms of adrenal fatigue are so general, they can apply to many diseases or conditions (depression, sleep apnea, fibromyalgia, hypothyroidism, or many other conditions) that stem from everyday life. And the society says some of the treatments can be dangerous.

What do doctors prescribe for adrenal fatigue? ›

Hydrocortisone (Cortef), prednisone (Rayos) or methylprednisolone (Medrol) to replace cortisol. These hormones are given on a schedule to act like the changes in cortisol levels the body goes through over 24 hours. Fludrocortisone acetate to replace aldosterone.

What can I drink for adrenal fatigue? ›

Naturopathic specialists often recommend specific treatments to support the adrenal glands and "heal" adrenal fatigue, including adrenal co*cktails. An adrenal co*cktail is usually made with orange juice, coconut water, and sea salt.

What vitamin calms the adrenal glands? ›

Vitamin B5 (Pantothenic Acid):

Certain B vitamins, including Vitamin B5 (Pantothenic Acid) provide targeted support to the adrenals. As studies show, B5 supports balanced cortisol production and helps reduce levels of excess cortisol triggered during stress events.

Where is the pain located with adrenal fatigue? ›

Abdominal pain or pain in your side (flank). Long-lasting fatigue. Loss of appetite. Darker patches of skin (hyperpigmentation).

What is a good breakfast for adrenal fatigue? ›

Try to include a good balance of protein, healthy fats, and carbs with every meal and snack to keep your blood sugar steady. Here are some ideas to paint a picture: Breakfast: scrambled eggs (protein), sauteed spinach and onions (carb), & sliced avocado (fat)

Why are bananas bad for adrenal fatigue? ›

Fruits lower in sugar are better options than the more sugar-laden choices like grapes and bananas. High sugar fruits have increased levels of potassium and fructose, which can add to the imbalance of the function of the adrenal glands.

Can adrenal fatigue be reversed? ›

B vitamins, such as B5 can help balance hormones, and reverse symptoms of adrenal fatigue in the body. Lack of sleep is another stressor on the body. By not getting enough sleep, your cortisol levels will rise and your adrenal glands will work overtime. More sleep will reduce cortisol and stabilize your adrenal levels.

How to detox your adrenal glands? ›

Eat a Balanced Diet: A nutrient-rich diet with plenty of fruits, vegetables, whole grains, and lean protein can help support adrenal health. Avoid processed foods and sugary snacks. Exercise Regularly: Exercise is an effective way to reduce stress and improve adrenal function.

What is the most common cause of adrenal crisis? ›

Risk factors for adrenal crisis include physical stress such as infection, dehydration, trauma, or surgery, adrenal gland or pituitary gland injury, and ending treatment with steroids such as prednisone or hydrocortisone too early.

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